OpenAI 与 Scripps Research 用数千个智能体 32 分钟完成小鼠全脑 CRISPR 图谱分析
OpenAI agents analyze mouse brain data in 32 minutes, a job that would take humans months
OpenAI 与 PerturbAI、Scripps Research 合作,用数千个基于 GPT-Rosalind 的智能体在 32 分钟内完成对数百万小鼠细胞的全脑 CRISPR 图谱分析,人工估计需数月至一年。
OpenAI teamed up with PerturbAI and Scripps Research to deploy thousands of AI agents that analyzed biological data from millions of mouse cells. According to OpenAI, the agents ran on GPT-Rosalind and worked through a whole-brain CRISPR atlas, which maps how gene changes affect different cell types in the mouse brain.
The full analysis took 32 minutes. Each agent took on a single gene perturbation, analyzed how the cells responded, and searched the scientific literature for explanations. The team estimates that doing the same analysis by hand would take anywhere from several months to a year.
Among other findings, the agents turned up unexpected differences between two disease-related genes and a possible link between cholesterol regulation and neurodegeneration. In blind comparisons, human experts preferred the distributed agents' reports over those from a single agent 75 percent of the time. The resulting "Reasoning Atlas" is available on GitHub, and the accompanying paper is out on bioRxiv.
OpenAI says these leads should help researchers decide which mechanisms to test in the lab first.
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来源:The Decoder:AI News · the-decoder.com