Model misalignment, prompt injection, or operator misuse could lead AI agents operating frontier-lab accounts to exfiltrate model weights, poison training data, or weaken release gates. Existing benchmarks do not test whether defenders can detect this activity among routine work under a limited review budget. We introduce MOLE, an open benchmark of 150 AI-operated accounts sharing 9 stateful services over 30 workdays, with 12 threats and 8 corpora from four models totaling roughly 20 billion tokens. Of 39 agent models, 72% complete most assigned harmful objectives and agent refusal does not predict completion. MOLE enables comparison of 40 monitors across corpus generators, observability levels, and threats; even the best evaluated monitor in our single-day audit-event comparison misses nearly half of completed harm. MOLE also enables monitor development: benchmark-guided search improves a mid-tier monitor by 49-64%, while selective use of a stronger monitor improves budget-AUC by 10% over applying it to every account-day at comparable modeled cost.